The Mucosal Immune System of Teleost Fish

The Mucosal Immune System of Teleost Fish

Teleost fish possess an adaptive immune system associated with each of their mucosal body surfaces. Evidence obtained from mucosal vaccination and mucosal infection studies reveal that adaptive immune responses take place at the different mucosal surfaces of teleost. The main mucosa-associated lymphoid tissues (MALT) of teleosts are the gut-associated lymphoid tissue (GALT), skin-associated lym...

Inside the Mucosal Immune System

An intricate network of innate and immune cells and their derived mediators function in unison to protect us from toxic elements and infectious microbial diseases that are encountered in our environment. This vast network operates efficiently by use of a single cell epithelium in, for example, the gastrointestinal (GI) and upper respiratory (UR) tracts, fortified by adjoining cells and lymphoid...

Current knowledge on the melatonin system in teleost fish.

Melatonin is a much conserved feature in vertebrates that plays a central role in the entrainment of daily and annual physiological rhythms. Investigations aiming at understanding how melatonin mediates the effects of photoperiod on crucial functions and behaviors have been very active in the last decades, particularly in mammals. In fish a clear-cut picture is still missing. Here we review the...

Lymphoepithelial interactions in the mucosal immune system.

The efferent limb of secretory immunity depends on local production and selective epithelial transport of polymeric immunoglobulins (pIg). To this end there is a fascinating cooperation of the B-cell system and the epithelium with their production of two key factors, the J chain and the secretory component (SC), respectively. Interactions between activated leucocytes for example, T cells and ma...

The Mucosal Immune System: Modulation by Microemulsion